Ergot Extract

Uses

• Obstetrics and Gynaecology:
• Postpartum Haemorrhage (PPH)
• Management of Third-Stage Labor
• Uterine Atony
• Historical Uses
• Neurology (Headache Management):
• Migraine Headaches
• Vascular Headaches
• Endocrinology:
• Hyperprolactinemia
• Acromegaly
• Geriatrics & Neurology:
• Senile Dementia/Cognitive Decline
• Parkinson’s Disease

Benefits

• Obstetrics and Gynaecology:
• Postpartum Haemorrhage (PPH): Prevention and control of uterine bleeding after childbirth.
• Management of Third-Stage Labor: Used to facilitate the separation of the placenta.
• Uterine Atony: Used to help the uterus contract.
• Historical Uses: Previously, it was used to induce abortions and treat menorrhagia (heavy menstrual bleeding).
• Neurology (Headache Management):
• Migraine Headaches: Ergotamine and Dihydroergotamine (DHE) are used to treat acute, severe migraine and cluster headaches. They act by constricting dilated blood vessels in the brain.
• Vascular Headaches: They are used when triptans are ineffective, typically as a second-line treatment due to side effects.
• Endocrinology:
• Hyperprolactinemia: Bromocriptine (a semisynthetic ergot derivative) is used to control high levels of the hormone prolactin, treating conditions like galactorrhea, infertility, and prolactin-secreting tumors (prolactinomas).
• Acromegaly: Used in the management of acromegaly (excess growth hormone).
• Geriatrics & Neurology:
• Senile Dementia/Cognitive Decline: Dihydroergotoxine (ergoloid mesylates) has been used to treat symptoms of idiopathic mental decline in elderly patients, although its efficacy is considered moderate.
• Parkinson’s Disease: Pergolide and cabergoline (ergot-derived dopamine agonists) have been used in the treatment of Parkinson's.

Specifications

Frequently Asked Questions