Boswellia serrata Extract

Joint Health & Arthritis Management:

Osteoarthritis (OA)

30% AKBA extracts significantly reduce joint pain, improve physical function, and stiffness in osteoarthritis patients, with noticeable results often appearing within 7 days.

Rheumatoid Arthritis (RA)

It reduces inflammation in collagen-induced arthritis, lowering joint swelling (paw volume) and protecting the extracellular matrix (cartilage).

Chronic Inflammatory Conditions:

Inflammatory Bowel Disease (IBD)

Used to treat chronic colitis, ulcerative colitis, and Crohn’s disease by reducing tissue damage caused by chronic inflammation.

Bronchial Asthma

Used in managing asthma due to its leukotriene-inhibiting properties.

Cancer Support & Research:

Antiproliferative Agent

AKBA demonstrates anticancer potential by inducing apoptosis (programmed cell death) and inhibiting migration/invasion of tumor cells in cancers such as glioblastoma (brain tumors), prostate cancer, colon cancer, and melanoma.

Multidrug Resistance (MDR) Reversal

It has been shown to sensitize taxol-resistant ovarian cancer cells to chemotherapy, potentially reversing resistance.

Skin Health & Dermatological Applications:

Topical Anti-inflammatory

Used in lotions and creams to treat eczema, psoriasis, dermatitis, and acne due to its powerful anti-inflammatory, antimicrobial, and antioxidant properties.

Anti-Aging & Skin Protection

Reduces collagenases (enzymes that break down collagen), helping to maintain skin elasticity, firmness, and protect against photoaging.

Neurological Protection:

Neuroinflammation

AKBA has shown potential in alleviating neuroinflammation, promoting nerve repair/regeneration (e.g., in sciatic nerve injury), and protecting against ischemic brain injury.

Metabolic Health & Hepatoprotection:

NAFLD/NASH

AKBA alleviates Non-Alcoholic Fatty Liver Disease (NAFLD) and NASH by inhibiting Monoacylglycerol Lipase (MGLL) activity, reducing hepatic lipid accumulation (steatosis), and decreasing inflammation and liver fibrosis